Nepal | January 16, 2021

Novavax begins mid-stage study of COVID-19 vaccine in South Africa

Reuters
Share Now:

DURBAN: US drug developer Novavax Inc said on Monday that it is starting a mid-stage study of its experimental COVID-19 vaccine in South Africa, as the country experiences a surge in coronavirus cases.

The Phase 2b trial study of NVX-CoV2373 will be conducted on about 2,665 healthy adults and will evaluate the safety and immunogenicity in about 240 medically stable, HIV-positive adults, the company said in a statement.

“Because South Africa is experiencing a winter surge of COVID-19 disease, this important Phase 2b clinical trial has the potential to provide an early indication of efficacy, along with additional safety and immunogenicity data for NVX-CoV2373,” said Novavax research chief Gregory Glenn.

South Africa is fifth worst affected country with 583,653 coronavirus cases and 11,677 deaths, according to a Reuters tally.

The Bill & Melinda Gates Foundation is providing a $15 million grant towards the clinical trial, the company said.

Novavax said it intends to initiate the Phase 2 portion of this trial in the United States and Australia in the near future and that it would include about 1,500 candidates.

Earlier this month, Glenn told Reuters the company would start much larger late-stage clinical trials soon and could potentially glean enough data to obtain regulatory approvals as early as December.

The US government in July had awarded Novavax $1.6 billion to cover testing and manufacturing of a potential vaccine for the novel coronavirus in the United States with the aim of delivering a 100 million doses by January.

Last month, AstraZeneca said late-stage trials of its experimental drug AZD1222, which is developed by AstraZeneca and Oxford University, are under way in Brazil and South Africa and due to start in the United States, where prevalence is higher.


Follow The Himalayan Times on Twitter and Facebook

Recommended Stories:

More from The Himalayan Times:

First Arab Ama Dablam Expedition makes successful attempt on Thursday

KATHMANDU: A team from Seven Summit Treks ‘First Arab Ama Dablam Expedition’ comprising Qatari climber Fahad Badar, Sherief Elabd from Eygpt and Nadhira Al Harthy from Oman have attempted Mt Ama Dablam (6812 m) on January 14. The winter ascent to Ama dablam consisted of at least 14 climbers w Read More...

Biden unveils $1.9T plan to stem COVID-19 and steady economy

WILMINGTON, DELAWARE: President-elect Joe Biden unveiled a $1.9 trillion coronavirus plan Thursday to end “a crisis of deep human suffering” by speeding up vaccines and pumping out financial help to those struggling with the pandemic’s prolonged economic fallout. Called the “American Read More...

Mobile data users abandoning Ncell for NT

KATHMANDU, JANUARY 14 Mobile data users in the country are increasingly abandoning Ncell and subscribing state-owned Nepal Telecom. At least that is what the data compiled by Nepal Telecommunications Authority reveals. According to the Management Information System of NTA, 60 per cent of the t Read More...

Rival NCP factions hold standing committee meetings

KATHMANDU, JANUARY 14 Nepal Communist Party (NCP) led by Pushpa Kamal Dahal and Madhav Kumar Nepal held its Standing Committee meeting and discussed ways to effectively carry out its protest programme against dissolution of the House of Representatives. NCP (Dahal-Nepal) Spokesperson Naryan Ka Read More...

Security personnel of Khotang District Police Office destroy cannabis planted illegally by the locals in Durchim VDC of Khotang district on Monday, December 21, 2015. Photo: RSS

Cops intensify drive to destroy cannabis, opium plants

KATHMANDU, JANUARY 14 Nepal Police destroyed cannabis and opium plants cultivated in a large swathe of land across the country in the fiscal year 2019-20, according to an annual report recently released by the Ministry of Home Affairs. According to the report, cannabis plants being cultivated Read More...

WHO supports member countries to end COVID-19 pandemic

KATHMANDU, JANUARY 14 Member countries in the World Health Organisation South-East Asia Region are gearing up for massive vaccination campaigns in a bid to end the COVID-19 pandemic. The WHO South-East Asia Region has 11 member countries — Bangladesh, Bhutan, Democratic People’s Republic o Read More...

Bhattarai calls for decisive agitation

DAMAULI, JANUARY 14 Janata Samaj Party-Nepal Federal Council Chairperson Baburam Bhattarai has stressed the need of a decisive struggle to protect democracy and the constitution. Accusing Prime Minister KP Sharma Oli of putting the constitution and democracy at risk by dissolving the Parliamen Read More...

Locals protest East-West Railway survey

BARA, JANUARY 14 The locals have protested a survey of the East-West Railway in Bara. The locals were up in arms after a survey was done affecting the main settlement in the bazaar area of Nijgadh Municipality. According to the survey team Incharge Suraj Poudel, the locals impeded the d Read More...