Khris Middleton had 21 points and Giannis Antetokounmpo added 17 points and 15 rebounds to lead Milwaukee, which had its four-game winning streak snapped.

Minnesota, which entered the game with four losses in the past five games, dominated from early in the second quarter.

The Timberwolves led by double-digits minutes into the second quarter and increased the margin to 23 on the first play of the third quarter on an Andrew Wiggins alley-oop dunk from Jeff Teague. Milwaukee trimmed the lead to as little as 15, but the Timberwolves built the lead back up to 20 down the stretch.

The Timberwolves shot 54 percent from the field and held the Bucks to 38 percent shooting, with Milwaukee finishing just 21 percent (6 of 29) from 3-point range. Towns and Butler were both efficient from the field -- Towns hit 10 of 13 and Butler made 8 of 15.

Milwaukee, which expects to get starting forward and former No. 2 pick Jabari Parker back Friday from a year absence caused by a torn ACL, lost starting point guard Malcolm Brogdon to a left quad strain in the second quarter.

Brogdon's backup, Matthew Dellavedova, finished with zero points in 25 minutes.

Minnesota cruised to the win despite having just Towns and Butler in double figures. Wiggins finished with just seven points, but five Timberwolves had either eight or nine points, including Teague, who had nine points to go along with his eight assists.

Milwaukee claimed the battle of the boards, 43-39, but the Timberwolves outdid the Bucks in assists, 27-19, and had seven blocks compared to one for Milwaukee.

The 19-point loss was the Bucks' second big defeat in six games, following a 116-94 setback at Philadelphia on January 20.

The Bucks host the New York Knicks on Friday. Minnesota hosts the New Orleans Pelicans on Saturday.