LONDON: The Special Relationship has seen its second dropout - Julianne Moore has been forced to quit her role as former U.S. First Lady Hillary Clinton due to scheduling conflicts.

Moore was set to star alongside Dennis Quaid, who will portray ex U.S. President Bill Clinton in the new movie, about the professional relationship between the charismatic leader and former U.K. Prime Minister Tony Blair.

However, Moore has had to step down from the role due to other work commitments, just weeks after original director Peter Morgan also pulled out of the project.

Actress Hope Davis will now step into Moore's shoes, while British filmmaker Richard Loncraine has signed up to take over from Morgan.

Frost/Nixon star Michael Sheen will once again reprise the role of Blair, after he received high acclaim for his portrayal of the former British leader in Oscar-winning movie The Queen.